Welcome to the Manis Lab at UNC Chapel Hill. We study how sensory information about sound is processed in the brain, at both a cellular and network level. We use experimental approaches that investigate ion channels, synaptic transmission in both excitatory and inhibitory synapses, network connectivity, as well as computational models. Our interests include studies of the earliest stages of central auditory processing, in the cochlear nucleus, as well as processing in auditory cortex, in both normal hearing and under conditions of defined hearing loss.